Saturday, 27 August 2016

Thought-Controlled Nanoscale Robots in a Living Host

Nanoscale Robots

A strategy life like

A man has been able to control nanorobots residing inside living things with the sole use of his thoughts for the first time. The equipment released a drug within the cockroach in reaction to the man’s brain action – a strategy that may be of help for curing disorders related to the brain like ADHA and schizophrenia. Getting drugs to the target site could be a great challenge.

A majority of drugs are spread in the body or transported via the blood stream over time –and you have to helplessly bear the side effects in anticipation of the drug to wear off. Two groups in Israel, one in Ramat Gan and another in Herzliya called, Bar Ilan University and Interdisciplinary Centre respectively, have come up with a scheme that permits specific control when a drug is not passive in the body.

The team has constructed nanorobots with the help of DNA, creating shell-like figures that drugs can be secured in. These bots have gates which bear locks formed from nanoparticles of iron oxide. With the help of the heat formed using electromagnetic energy, the lock can be opened up and the drug can be exposed at the target site. Since the drug stays bound to the DNA, the opening and closing of the gate controls a body’s exposure to the drug.

Mind medicine

In order to make the DNA bots respond to the thoughts of a person, the group educated a computer algorithm to differentiate between a human’s brain activity when at rest and when conducting mental arithmetic. The group then introduced a luminous drug to the bot and was injected into a cockroach which sat in an electromagnetic coil.

An EEG cap was given to a person to wear that measured brain activity, either stay at rest or to conduct calculations mentally. The electromagnetic coil was connected to this cap, thus powering it on when the person calculated and off when he was at rest. The team confirmed that the technique worked by observing as to when the luminescence was shown inside several cockroaches.

A member of the team at the Interdisciplinary Centre, Sachar Amon says that the algorithm could be more skilled to track down other forms of activity of the brain. “It is possible to tracecircumstances of the brain which could be responsible for schizophrenia or ADHD, for instance. It could be revised to suit the needs of the individual.”

The clue would be to spontaneously activate the release of a drug when in need. Take for instance; people would not always know as to when they would need medication – prior to an intense occurrence of schizophrenia. If it could be detected by an EEG that it was to arrive, it would probably stimulate the discharge of a preventive drug.

Triggered release

The mechanism should be able to reduce the unwanted side effects that come along, since the bots can conveniently close and open their gates as per requirements. Fine tuning the DNA bots could also give assurance that they would be target specific regarding to the cells in the body, therefore subsidizing harmful reactions elsewhere within the body.

This could be achieved by fastening molecules that could bind to receptors on the exterior of definite types of cells to the surface of the bots. But this kind of scientific machinery is not yet ready to be tried in humans.

The formation needs a smaller, more transportable process of quantifying brain activity; something Amon believes is not a long way to go. The group sees a person wearing a tiny, EEG device which looks similar to that of a hearing aid, to keep note of brain activity and identify when a drug would be needed.

An example would be, when a person having ADHD, has a concentration which is about to lapse, the electromagnetic field necessary to discharge the drug dose of Ritalin would be triggered by a smart watch creating it. Such type of permutations of various devices could come of aid to treat the depressed and other people suffering from conditions of the brain that could be a great task to deal with.

Not only that, but it would also permit people to consciously trigger when they willingly want a drug to be discharged by calling upon particular thoughts. Again when asked Amon commented that, “This could be directed by people in various orders. Picture if you could supply the precise amount of alcohol that you would wish to keep yourself in a joyful state but not too much to be drunk. It is kind of silly, but such things are possible and can take place.

I think so far we have initiated the briefest research to discover something concealed.” In no time, they would possibly hit the ground running and so would be those who are schizophrenic and suffering from ADHD.

Thursday, 25 August 2016

Knuckle-Cracking is Actually Good For You


Of Myths and Results

Tanya Johnson is an outstanding nurse, but has been driving her boss, Dr Robert Szabo nuts for 15 years with her never ending knuckle cracking which makes him want to choke her. Szabo is the former president of the American Society for Surgery of the Hand and is also a hand surgeon at the UC Davis Medical Centre. Johnson was constantly told by Szabo to stop with the cracking of her knuckles by saying it wasn’t good for her to which she replied asking him to prove it. But Szabo was unable to.

When Dr Robert Boutin, his colleague who is a radiologist at the same centre asked him to work together on a knuckle-cracking study, Szabo grabbed the opportunity. They together gathered people, along with Johnson herself, who were driven with the needed habit, and perform the action under ultrasound so as to observe what really happened inside the joint. Not only were the knuckles examined before and after the cracking of them, but also the knuckles of a number of those who do not crack their knuckles were also considered, to observe problems inclusive of swellings and weakened grip strength.

Szabo felt certain that the test would prove to his nurse that the cracking of her knuckles had to stop as it was bad. But this didn’t fall in his favour. They found no hand problems in those who cracked their knuckles frequently. As a matter of fact, when a knuckle was cracked, the individual showed an increased range of movement as compared to those whose knuckles hadn’t cracked. The study was presented at a meeting in December of the Radiological Society of North America, although it has not been published.

What causes the crack?

More than simply knowing the pros and cons of knuckle cracking, Szabo and Boutin were keen to know what exactly happened inside the joint that had been cracked. The researchers found something remarkable, by looking at the ultrasounds of around 400 knuckles. They found that when a knuckle was cracked, there was characteristic and a sudden flash in the joint.

They though that when a knuckle is cracked, two surfaces of the joint is being pulled apart, which lowers the amount of pressure in the joint. That pressure lets gas which is mixed with the fluids within the joints to be liberated, and the bright flash observed is a bubble of gas forming. Boutin says that he thinks that is why a joint has more motion post cracking. Maybe lowering the pressure permits the joint to be a little loose and relaxed.

The mythology behind knuckle-cracking

If knuckle cracking is proved to not be bad for you, then how did it come around with a negative approach? A rehabilitative medicine specialist, Dr Greg Kawchuk at the University of Alberta said that, everybody’s aunts and grannies say that it isn’t a good practice, but no one has an idea where that comes from. He mentioned he might know it, based on the fervent reply he received when he published his very own study on knuckle cracking last year.

He also said that they got feedbacks from a lot of people and while a few said that they felt relieved by cracking their knuckles just as many found it pretty disgusting. Perhaps, this could be the reason why generations of grannies and aunts have corrected children to stop with the practice because they simply couldn’t bear the sound. It was his person opinion, but he felt that few of the people felt gross because of it that they created such myths. But this myth does have a scientific side.

A study from 1990 showed that knuckle crackers were more prone to have swelling hands and bad grip strength. But Kawchuk and Boutin pointed out some flaws in the study from more than a one fourth of a century ago. First, if the researchers knew which individual cracked knuckles and which did not and not having known that could have made their evaluations biased.

Secondly, the writers did not maintain transparency as to how they judged grip strength and swelling. Be that as it may, Szabo and Boutin are the first to say that their test wasn’t a final study on cracking knuckles, especially as they observed only short term and not prolonged effects. They say that in the coming years, a greater and better study may refute their findings.

Boutin typed an email saying ‘Knuckle kerfuffles are numerous’ adding an emoji of a smiling face at the end of the sentence. But in the bargain, it clicked to Szabo that he has no valid reason telling his nurse to put an end to cracking her knuckles. He said at the end, that after he reviewed the science behind it, he had a strong opinion that knuckle cracking was on the whole not harmful.

Wednesday, 24 August 2016

'Bagpipe lung' warning for wind musicians


Harbouring in the damp

In the journal Thorax, UK doctors warn that people who play wind instruments like bagpipes, trumpets and saxophones can have damaged lungs. They explained an unusual but deadly scenario in a patient who was 61 years old, called ‘bagpipe lung.’ The late man is believed to have cultivated a reaction against fungi and moulds prowling inside the damp interiors of his bagpipes.

Doctors are advising others to be better sanitized. They recommend a routine clean-up of the instruments to avoid the growth of yeast and other microscopic organisms. If a player feels breathlessness and has a cough, he should ponder on the possibility that his symptoms could have been aggravated because of their practice in music.

Many other familiar reports have been documented with regards to trombone and saxophone players facing lung problems. Gratefully, the symptoms and caused were diagnosed at an early stage and were treated and cured at the earliest.

Irreversible scarring

Doctors explain that lung damage occurs when the immune system of the body get overridden. The pathogen that are inhaled cause inflammation, and if is not treated, can cause an increasing and irreversible scarring. The doctors at the Wythenshawe Hospital mentioned that they had an intuition that the person’s bagpipes could be the root of his problems.

The man was a dedicated piper and used to practice music daily. He had been sick for a few years, except for a few months when he went abroad and his bagpipes were left at home. They were then sent to the laboratory to be tested and prove the doctor’s intuition to be true. When the results came back it declared that the instrument was a haven for moist-loving fungi and mould, the ones that doctors are aware can cause problems related to the lungs.

The impairment that was previously done to the man’s lung was permanent as a result of which his condition worsened and led to his death. A member of the Wythenshawe group who had a role in this case called Dr Jenny King said that unfortunately the damage was lethal. If the diagnoses are predicted early and its activation could be stopped then these people can be cured and the prognosis is truly great. These pathogens are in the air around us but are not usually at a high possible standard to create problems.

This type of problems with respect to the lungs is seen especially with those who work on farms and work near or around plenty of mouldy hay. Andrew Bova is an expert bagpiper in Glasgow at the National Piping Centre. He suggests that he would certainly recommend giving the woodwind instrument a swab after every use when it comes to hygiene.

Moisture can settle in the nooks and corners and we wouldn’t want that. Moisture as it is damages wooden articles so a swab would do the work of keeping it clean. Andrew makes use of brushes to keep his blowpipe clean and shares that he also gives a complete rinse with hot water once in six months to avoid any possible problems in the future.

Monday, 22 August 2016

Golfers Have Unusual Hips, Study Suggests

Different joints

Researchers have recently found that golfers who play at a professional level are expected to have extraordinarily shaped joints of the hip. The team from The University of Warwick had selected 55 top players for medical MRI scans, and they were surprised with what they found.

The scans showed that right joint had an egg shaped hip and the left joints were generally in the shape of a ball. It was not clear whether such a deformity in both the joints of golfers was caused due to the sport, they mentioned in the British Journal of Sports Medicine. Nearly, one out of every five people of the 2015 Scottish Hydro Challenge experienced hip pain.

Professor Damian Griffin who is the lead researcher said that the mismatch in the shape between the hips could explain the reason why golfers experience pain. Specialist sports doctor, Dr Andrew Murray, for the European golf tour said that on a whole, we are aware that golf can give significant health benefits, along with possible upgraded durability and improved mental and physical health. However, golf puts great force on the hips every time the club is swung by the player.

Symptoms and causes

While a golfer swings his club, both the hips move in different angles and at different velocities. In 16% of right hips of right-handed golfers, the egg shape was visible on some of the scans near the rear hip, and 4% on the left hip during the swing of the club in players who played at a professional level.

This condition caused by the action is known as cam rotation, which decreases the natural angle of movement of the hip. Dr Edward Dickson, a co-researcher said that their results found out new questioned to find answers to. What is left to be found out is whether the professional players cultivate these shapes due to the way they angle their hips and also the movement of them or whether the golfers with these hip deformities are more prone to play at a professional level.

The hip pain caused due to constant playing of the sport is due to the large amount of pressure built up not only on the joint but also its surrounding muscles when the player swings the club. The outer rotation of the hip area during a swing can induce a tremendous strain on the joint and the surrounding part when practiced often, as professional players do on an average an 18 whole course.

The speed at which the club is swung can also be another reason of stress caused on the hip if the swing is not precise or even. The pain may persist in the hip and pelvic region of the player’s body and may arise from overstretching of the joint. It also has a chance of increasing during actions which involve twisting. Situations where a catch in the hip joint when tries to change position, for instance, when getting up from a sitting position can also be experienced by professional golfers.

Injected Drug May Help Fight Osteoporosis in Women


New Drug – Decrease Risk of Bone Fractures – Women with Osteoporosis

A latest study has found a new drug which is said to decrease the risk of bone fractures in postmenopausal women having osteoporosis, much better than a placeboand the drug is presently made available. In this stage three trial supported by the maker of the drug, Radius Health, less women on the injectable drug abaloparatide had spine fracture than women who received a placebo and somewhat less than those taking the same injectable drug, teriparatide.

In the case of postmenopausal women having osteoporosis with the risk of fracture, regular injection of the drug abaloparatide for a period of 18 months significantly could reduce the risk of new vertebral as well as non-vertebral fractures when compared with placebo as per a study in the August 16 issue of Journal of the American Medical Association - JAMA.

Osteoporosis is linked with considerable economic, social and public health problems and based on the 2010 U.S. Census data; the study has estimated the prevalence of osteoporosis in women between 50 to 69 years, at 3.4 million. It has also been assessed that the lifetime danger of osteoporotic fracture for a 60 year old women is said to be 44%. Moreover, therapies are essential in the prevention of osteoporotic fractures.

Abaloparatide/Forteo – Synthetic Peptides

Lead researcher, Dr Paul Miller of the Colorado Centre for Bone Research had informed that if they get the approval then this would be the second drug which would be available in treating high-risk osteoporosis. He believes that Forteo had been used for the past 16 years.

 Abaloparatide tends to work differently from Forteo and recovers bone density more than Forteo. Miller also mentioned that several spine fractures are painless and the patients are frequently unaware about it till a doctor tends to measure their height and finds that they are up to an inch shorter than before.

Miller informs that Abaloparatide and Forteo are both synthetic peptides which seem to assist in growth and strengthen the bone.He adds that together with the construction of bone density, they are also the only one which tends to increase the quality of the bone and bone quality is an important feature of bone power, the capacity to survive a breakdown.

Need of Large Head-to-Head Trail between Forteo/Abaloparatide

He envisages that when abaloparatide is on the market it would compete with Forteo, bringing down the price of both the drugs. Miller had informed that he is hoping to have a second drug available which would help in reducing the cost.

The cost of Forteo is around $2,500 a month if one does not have insurance. And if a patient is insured, the monthly co-pays could range from $30 to $400. Forteo is said to be covered by Medicare.The director of the Centre for Pituitary and Neuroendocrine Disorders at Lenox Hill Hospital in New York City, Dr Caroline Messer is keen for further study.

She informed that there is a need of a large head-to-head trail between Forteo and abaloparatide to actually see which drug could be better. She added that everybody wants to know if this is inferior or superior to Forteo. This being an early study, it shows more bone building and fewer fractures than Forteo though whether it would replace that drug is still uncertain.

An editorial associated with the study stated that which drug is selected may be less important than recognizing and beginning an accepted treatment.

How Alcohol Consumption and Alcoholism Are Affecting Young Individuals

How Alcohol
Most individuals are interested in scientific studies that relate to their life somehow. However, not everyone is always completely convinced that a study proves a point one way or another, especially if the study was short. Many individuals have shown an interest in a recent study that was completed by the Baker Institute for Public Policy, which is in association with Rice University. They have released the results of a 40 year study that proves that alcohol is a gateway drug. It underscores the importance of helping alcoholics enroll in an alcohol detox program to get the help they need.

This study revealed many interesting facts. One of the interesting things that this study pointed out is that most individuals begin experimenting with alcohol when they are young teenagers, some as young as 12 years old. Even though there is no doubt about the fact that illicit drugs are addictive and cause a wide variety of problems for addicts, the study showed that alcohol can do far greater damage. This is especially the case when an individual begins drinking alcohol when they are young.

There are many factors that may contribute to individuals beginning to drink alcohol when they are young. Some say that advertisements that promote alcohol use are partially to blame. It is true that in addition to the fact that alcohol is advertised online, on television, in magazines, and in other areas, alcohol consumption is usually painted in a good light. It makes an individual look cool, like they can fit in socially, and like they can relax and just be themselves. Of course, drinking in moderation is not always a problem. However, since alcohol is an addictive substance for many, when individuals begin to consume alcohol when they are very young, it can lead to a life of addiction.

One of the very best steps to help individuals, no matter their age, it is education. Most young individuals taste their first sip of alcohol from their parents. And, of course, each parent has the right to provide alcohol education to their child, but part of this education needs to be helping their child understand the dangers that can come from over drinking and the potential for alcohol addiction as they get older. Thankfully, more and more information is becoming available and the topic of alcoholism is becoming something that is easier to talk about. These and other factors are making it easier for individuals to enroll in detox programs and begin a recovery journey.

For many people who are addicted to alcohol, getting the help they need begins with admitting they have a problem. This can be one of the most difficult steps that an alcoholic can take. However, when they realistically look at what alcohol has done to their life, how it has affected their career, and how it has affected their family, they begin to see that they need to make changes in their life if their life is going to get better.

Deciding on a recovery program does not need it to be a challenge. Detox and recovery programs are going to vary from location to location. However, most of them are going to help an individual get to the root problem of their alcoholism or their drug addiction. Most emphasize the importance of therapist in recovery. This is something that is extremely important because the vast majority of individuals who overindulge in alcohol and who are addicted to it do not do so for fun. It is something that they turn to when they are depressed or experiencing problems in their life. Therapists will be able to help the individual recognize these problems and then take steps to avoid them during their recovery.

Some individuals feel nervous about enrolling in a detox and recovery program. They think that it may be embarrassing for them to talk about the problem with their family, their coworkers, or other individuals in their community who may find out about their problem. First, you should know that the work that takes place in detox and recovery programs is confidential. Second, even if other individuals find out about your problem with alcohol, they are likely going to applaud you for taking steps to recover. Third, you should know that you are working with caring individuals who are licensed and trained professionals. They will help you get through detox and walk with you as you are on your journey to sobriety.

Viruses 'More Dangerous in the Morning’

Morning sickness 

Studies conducted in University of Cambridge suggest that Viruses could be more hazardous when they come in contact with their victims in the morning. As published in PNAS, the findings showed that these viruses could be more successful up to 10 times if the infection began in the morning.

Tests with animals showed that an interrupted body clock which can be caused due to being jet lagged or working in shifts can always be prone to the infection. Scientists believe that these findings could lead to ways of ending pandemics. Unlike parasites and bacteria, viruses completely depend on taking over the mechanism inside the cells so as to replicate. However, these cells change vividly as a portion of a 24 hour cycle termed as the body clock.


For the study, mice were either exposed to influenza or herpes virus, which caused flue or a range of diseases including cold sores respectively. The viral intensities of those that were infected in the morning were 10 times more than those that were infected in the evening. After continuously trying to hijack the cells, the late viruses efforts were waning after all the labourers had gone home.

One of the researchers, Professor Akhilesh Reddy, spoke with BBC news website stating that there is a big difference. If the virus does not get all the mechanisms readily available, it may not get off the ground ever. Even a small amount of infection in the morning could propagate faster and take control of the body. He is certain that the results can help control an epidemic of diseases.

In a condition where a disease is prevailing over a country, staying indoors during the day could be important and save people from being infected. Further studies showed that the animal’s body clock being disrupted intended that they were being trapped in to a state that allowed the viruses to grow and spread. The first author, Dr Rachel Edgar said that this is an indication that people who work in shifts, that is, working during some nights and rest for some nights have a disturbed body clock, are susceptible to be infected to viral diseases.

Then they could be major applicants for receiving the yearly flu vaccinations. Only two types of viruses were used for the study. Yet the two very different one being a DNA virus while the other an RNA virus. Which directs the researchers to believe the morning threat may be a wide range principle that spreads across a large number of viruses.

The study was focused on a particular clock gene, Bmal1, which has its topmost activity in the noon in both, people and mice. Professor Reddy added that it is the link with this gene that is vital, since it is low early in the morning one could be liable to the infection. Interestingly, during the winter Bmal1 is less active, indicating that it may have a hand in the larger risk of infections at that particular time in the year.

Thursday, 18 August 2016

Women Warned about Booming Market in Period Tracker Apps



The market is flourishing with apps which grant women an opportunity to keep in check their dates of their month menstrual cycle. Currently, 200m download are thought to have been of menstrual cycle tracking apps, throughout the world. However, one of the top UK medical royal college has notified that women should not completely and blindly depend on these apps as a form of contraception.

Promoters of privacy suggest that users should be cautious of what matter they might unintentionally be sharing when they download such apps. When one searches for apps which track one’s period one will see lot of options being prompted like some displaying charts and diagrams, while others illustrate floral patterns of lilac or pink tulips. Menstrual cycle tracking apps come second to apps which are based for motor running, in the category for health and fitness.

Amy Worsfold resides in the south-eastern part of London in Greenwich mentioned that she used multiple trackers for about three years. This opera singer said that when a woman is in a pre-menstrual phase, the levels of hormone secretions are elevated and affect the larynx in different ways could be unfavourable to the same person’s singing voice. She makes use of such apps just to avoid fixing auditions, important performances or premiers on pre-menstrual days if she could.


She notes down and calculates her cycle with the help of her smartphone. The app also has feature which allows her to recognize connections with fluctuations in her emotions or mood, headaches and eating habits. She added that since she was able to make note of what was happening to her and how she distinctively responded to her cycle made her aware n could take ownership of the fact that could suck but also is completely necessary.

In some cases, women download apps to track their period in order to monitor their fertility. But Gynaecologists and Obstetricians from the Royal College have advised them not to use the apps as a way of contraception. So far, only one app in the market has solely assessed for efficiency for the same. Mostly they are not categorized as medical devices that would involve stern regulations.

Powerful tool

Clue is an app by Ida Tin, who is a Berlin based Danish entrepreneur. Her market share is of 10% in the UK. She said that all she wanted to do was develop a next generation of technology in the terms of family planning and she is certain that they will reach there, however they haven’t reached there yet. Many women have been recently showing a great amount of interest in Clue from Brazil and Mexico, probably due to the increasing threats of conceiving during an outbreak of zika.

Ida is fascinated in how anonymous matter from her app which is free can be used for a greater good. She has therefore teamed up with medical researchers who are established at Oxford University. Her business has been constructed on an accountable method by her.

She adds that her app is a very powerful tool, and that she cannot do what her users would want her to do until and unless she makes use of the data that they feed in. She is grateful and she is asking for a lot of faith in her, but many companies that likewise are in the same sort of work line, do not have any value or respect the trust they set.

Terms and conditions

Few apps that more clearly directed at conception have a proper value to advertisers and promoters. For instance, a woman who is planning for a baby will be a likely market for clothing, prams and other possible purchases. Sam Smith, who is privacy promoter at medConfidential said that it is necessary for a source to be present for people to trust which is independent and that can assure the safety of the app for individuals, not only for all medical applications, but for applications for conception in particular.

The terms and conditions which are provided but the app developers can be read; also legally people are required to do so. But every individual knows that nobody pays heed to that. Sam understands the deficiency of regulations or also authorized recommendations, as a failure of the market in this area.

As a result, he advises that in case the application is free of charge to download, one should ponder if they would have to be paying for it in result by providing them with their data that they feed in the app on their smartphone, and also consider where that would be going. This along with many other aspects calls for areas of improvement. Further improvement need to be made to gain accuracy. So far it’s all on trial and error, until the data can be examined by the developers.

Wednesday, 17 August 2016

Mental Health Target Being Ignored

Mental Health

Figures reveal that few psychological health patients in England are being deprived of appropriate treatment, as promised by the government. In April 2016 the target being to conduct thorough treatment within two weeks, was hosted, to offer mental health the same recommended importance as cancer. Figures from Freedom of Information propose that the target is being ignored by a one fourth of clinical commission groups. To be able to help meet the demands, NHS England said that it is spending more money in services.

Early intervention

The scheduled time target needs that any patient between the ages of 14 to 65 undergoing their first occurrence of psychosis, which is a mental health condition that can consist of illusions or hallucinations, are given treatment in two weeks of being referred. However, the FOI appeal shows that in a few areas this is not happening, which was sent in England to its 209 CCGs by the Liberal Democrats. Out of the 209, only 170 responded back. From the 170, 23% said that they had used the target to for 14 to 35 years old alone. And more than three fourth of them had no solid strategy to extend it the age group of 35 to 65 years within this year. The set of intensive treatment that must be provided, called as early intervention in psychosis or EIP in short, includes support for patients from a variety of health professionals, together with psychiatrists, nurses and social workers of mental health and must match the best practice draft confined in guidelines laid down NICE, the clinical watchdog.

Treatment based on evidence

The BBC saw documents which suggested that in one part of England, most mental health trusts were incapable of saying whether their care package had been distributed in line with the requirements of NICE. EIP may budget the NHS £8,250 for a patient per year, as estimated by NHS England. Around 64% of the CCGs that gave a reply back to the FOI demand had no idea or couldn’t comment what their expenditure on EIP were, additional 29% mentioned that they were paying less that £8,250 for each patient. In the meanwhile, 32% of the CCGs were unable to estimate what their overall decided expenditure for EIP would be for the current year. Norman Lamb, who is Liberal Democrat’s health spokesman, commented that, ‘across the country it is seen that people are not receiving the treatment which is based on proof, which is set out in the agenda.

Psychotic symptoms

It is as similar as telling a cancer patient that they can undergo chemotherapy, but they cannot go through radiotherapy. Sarah Broadbent, whose brother suffers from the same problem runs a campaigned and named it 25Percent, consequently named due to the fact that only one fourth of the population over the duration of any one year seems to have been a victim of a mental health problem. Matthew, her brother, experienced his first breakdown and mental health symptoms at only 18 years of age. For a period of 20 years since then, he has got a lot of care, both in and out of the hospital, which she labels as irregular at best and inattentive at worst.

Joy with a limit

At the beginning of Matthew’s mental illness, EIP had not yet been launched in the NHS. Sarah says had it only been readily available for her dependent brother, he entire life would have turned out to be very different. She didn’t indicate to that he would have been very successful in life, nonetheless he could still have gone on to life a life which is steady and gives him possible joy. Currently, her brother’s life is joy deficient, and a lifetime of 23 years gone by with inadequate joy and sheer irritation is a pretty gruelling way to exist.

Additional funding

The fact that the early intermediation can recover your educational and academic accomplishments can develop job chances and openings and as well as physical health is supported by a number of evidences. A representative from NHS England mentioned that now there will be additional backing in sense of expenditure for 10% extra people to be given treatment in two weeks, from the years of 2017 to 2018, which by the year of 2020 to 2021 builds up to £70m per annum.

The proof heaps up that these services will help the needful recover to full health and receive a good qualitative life. Countries like Wales and Scotland in UK have prior intervention programs for severe mental illness, but no value for waiting times for the treatment. On the other hand, Northern Ireland does not provide the people with services alike. Hence, there is yet a lot of progress to happen. Looking at the amount of budgeting, and attention this problem has received, it is possible that a lot more can be done as it is the need of the hour.

Tuesday, 16 August 2016

How 'Pokemon Go' is helping kids with autism and Asperger's

Pokemon Go

Pokemon Go Assist Children with Autism/Asperger’s Syndrome

Pokemon Go does not only entertain but the game also tends to assist children with autism and Asperger’s syndrome control in their developmental disabilities. The augmented reality game is said to enhance their social, decision-making as well the skills in solving problems.

The improved reality feature of the game, together with the method of rewarding player who tend to go to Pokestops placed at famous landmarks in their societies have led several players to be more interactive than earlier while playing the video games. When a twelve year old Ian Thayer had asked his mom to go outside for Pokemon hunting, Stephanie Barnhill at first had been surprised andexcited.Ian was suffering from Asperger’s syndrome and for him it meant struggling with social interactions and motivation while going out.

Barnhill frequently had difficulties in persuading Ian to leave his space to explore outside. He had also rejected Pokemon Go at first. However, Barnhill has informed that since he began flicking away and catching Pokemon, Ian has now started going outside more often and interacting with the other children and also with his community.

Pokemon Go Beneficial in Socializing with Other Kids

Barnhill informed that he has readily agreed to go out to Pokestops, get Pokeballs and catch creatures when earlier he seemed to be disinterested in going outside. He was not the type who would go out and play but this game had helped him to want to reach out to people and get into conversation regarding the creatures they have caught. Lenore Koppelman the mother of a six year old Ralphie having autism and hyperlexia which is linked with verbal language problems also noticed that Pokemon Go was beneficial in assisting her son in socializing with the other kids.

The kids get so engrossed in catching Pokemon that they tend to concentrate in discovering them more than they tend to concentrate on his behaviour as they generally tend to do. Koppelman has informed that the outcome is that her son is now found in the middle of groups of kids he does not even know and enjoys playing with them.

Shared Interest Sparked Changes

Although no assessable learning is done to the effects of Pokemon Go, Dr James McPartland, director of Yale’s Developmental Disabilities Clinic in the Child Study Centre has informed that the game seems to be appealing with the kids with autism or Asperger’s due to its consistency as well as structure. He stated that `Pokemon Go comprises of a limited set of interesting characters which is reliable and steady and kids with autism often like things that are like this which are list-based or concrete or fact-based.

They are very good at learning about things and memorizing things, so not only is this a shared area of interest, it is an area wherein the kinds of strengths with autism can shine’. As per a school psychologist in New York, Dr Peter Faustino, who does not tend to work with Ian or Ralphie, it is the shared interest which has helped in sparking changes in the kids with autism or Asperger’s. He has described how he tends to guide kids with Asperger’s or autism in adapting a social hook which he explains as `something which would share an experience or a connection’

Friday, 12 August 2016

Zika Linked to Baby Joint Deformities

Joint Deformities

The newfound problem

Experts fear that Zika infection experienced during gestation could cause deformed limbs in the baby. In the journal BMJ, seven questionable circumstances are described by Brazilian scientists from Recife, which is the city at the heart of the Zika epidemic.

The virus has not only managed to spread across more than America and prevented people from physically viewing the Olympic host nation but now has been causing a severe foetal brain defect. Pregnant women are advised to be cautious. Expectant mothers should not commute to area with Zika, and those living within such zones should avoid coming in contact with mosquitoes which are carriers for the disease. Researchers now come to an agreement that Zika is able to cause a long-lasting brain damage to developing foetuses in the womb.

The virus caused Zika can conveniently pass through the placenta from the mother to the foetus. And there is a budding proof that it can initiate an uncommon, weakening state of the nerves in adults, which is called Guillian-Barre syndrome. Dr Vanessa van der Linden and her team established in Brazil said that they are now come across limb joint problems and defects in new born children that could be a possible caused of Zika.

Zika outbreak

They studied seven babies alleged to have be exposed to Zika infection in the hospital, and had born that they were born with knee, elbow, wrist and or finger, hip joint problems that looked appropriate with a medical analysis called arthrogryposis.

The defects of arthrogryposis, (also called crooked joints) are results of faulty muscles; few too contracted or tight and some too relaxed, that have stretched and help the child’s developing body in abnormal positions. Dr. Linden’s team are dubious that the Zika virus affect nerve centres of the brain that supply the muscles around the joints, rather than the joint itself. This idea was supported when scans of the babies’ brain were studied.

All the seven babies that were examined were confirmed negative for
extra pre-birth infections, like HIV and rubella that could have been a probable cause of their defects. Most had limb deformities as well as microcephaly. She also said that, from the time she began writing up her findings, she came across 14 more children with problems alike and is running additional tests. From the London School of Hygiene and Tropical Medicine, Professor Jimmy Whitworth commented that while not solid evidence, the proof that Zika might to be blameworthy was “pretty enthralling.”

He added that, ‘Microcephaly is the most recognizable form of pre-birth infection with Zika, however it is becoming crystal clear that’s just a portion of the whole range of damage that the virus can cause. The challenge was putting an end to the spread of the infection and showing some concern for those who could possibly be affected in both the long term as well as short term.

Tests show that the present epidemic could be carried on for three to four years. They also suspect that there will be tens of thousands of new-born children who could be infected with Zika. Meeting their psychosocial and corporeal needs will be the actual challenge."

Thursday, 11 August 2016

One Drug is 'New Hope' for Three Killer Infections


Drug with Potential of Treating Three Fatal/Neglected Infections

Animal studies show that a signal drug has the potential to treat three fatal and neglected infections namely, sleeping sickness, chagas disease and leishmaniasis. These are infections caused by parasites that affect a great deal of people in the pitiable parts of the world and this study could be portrayed as a new hope for handling these infections. The findings were made by the analysis of three million compounds as reported in a journal called Nature. They are now running safety tests for the drug before conducting human trials.

Although, the three infections are all caused by parasites, the parasites caused these diseases are different. Scientist working on the tests say that it could be a possibility that one drug could be useful against all the three.

Causes, carries and casualties

  • Chagas disease is affected by the parasite Trypanosoma cruzi, and is commonly called American trypanosomiasis. The tsetse fly is a vector for the parasitic infection and is caused when this fly bites a human being. It causes enlargement of the digestive system and the heart which could be fatal. Mostly, the people in Latin America are affected by Chagas, but lately, this disease has now spread to various other countries. 
  • Leishmaniasis is a disease caused by the protozoan parasite Leishmania donovani. Abite from a sand-fly carrying this parasite can cause you this disease. There are three type of this form namely, cutaneous, mucocutaneous or visceral. There could be many symptoms caused depending on the area of the body which has been infected. Symptoms noticed are anaemia, fever, disruption of the mucosal lining of the mouth, throat and nose. People mostly belonging to Africa, Asia and America are affected by this disease. 
  • Sleeping sickness also commonly known as Human African trypanosomiasis. But it takes more than a common name from the coma caused to the host because of the parasite entering the brain. It is caused by the parasite Trypanosoma brucei, and the vector is a tsetse fly. This ‘kissing’ or assassin bug carries the parasite and people mostly living in sub-Saharan area of Africa.

Parasites Affecting Millions of People

Together, these parasites affect around 20 million people, and an approximate of 50,000 die each year, as stated by the team of researchers. Despite the fact that there are medications available to cure the infections, the costs are exorbitant and toxic, and these need to be administered intravenously via drips, making it unfeasible in underprivileged areas.

Scientists have tried and tested three million compounds to the ones that could exterminate several parasites in the lab, prepared by Novartis, a pharmaceutical company. One of these was then used as the base and that was then used as a ground for numerous modifications to make the actual one 20 times more effective.

They found that the upgrade which they coded as GNF6702 could cure Trypanosoma cruzi, Trypanosoma brucei and Leishmania donovani diseases found in mice. One of the established scientists at the University of York, Dr Elmarie Myburgh, said to the BBC News website that, ‘the speciality of this is the fact that is directing to all the three parasites; it has been conducted the first time thus making it special.’ To Myburgh it is more than a big deal, because he wants to make a difference, being in his field he wants to create a cure and he along with his team are working day and night so to get the cure to patients.

Myburgh also stated that, ‘there is very less encouragement to spend such a huge amount of money for curing these diseases as it is the poor who are affected but in large numbers.’ Additional tweaks to the compound are being processed as the research team believes it is always best to ensure safety before conducting human trials.

Recycling by fluke

The drug helps by attacking the proteasomes of the parasite and the structure recycles the protein that are of waste in the parasite. Remarkably, the chemical does not distress similar processes in cells of mammals. From the Genomic Institute of the Novartis Research Foundation, Richard Glynne, said that the proteasome being attacked was not by design but was more by fluke.

It had been speculated that the proteasome was identical across all species to cultivate a drug that would not be lethal to the patient. On the other hand, he mentioned that there may eventually need to be three separate medicines for the three diseases respectively, ‘Having a single drug for all the parasitic infection could turn out to be not a good strategy.

The biology of the infections is diverse. For instance, in sleeping sickness, the target area of the parasite is the brain, therefore a drug is needed that can get into the brain, so there are refinements that may be essential.’ The Wellcome Trust research charity helped fund this study. It’s director of innovation. Dr Stephen Caddick told BBC News website that, ‘the parasites are horrid, highly ubiquitous and affect the people who live in parts of the world that are struck by poverty. More progress needs to be made.

Tuesday, 9 August 2016

Asthma Pill 'Promising' for People with Severe Symptoms


A ray of hope for asthma patients

Initial study in the Lancet Respiratory Medicine journal proposed that adults suffering from severe asthma could be helped with an experimental pill. The drug called Fevipiprant was administered to these patients for a trial and reduced the inflammation within their airways. There were patients with uncontrolled asthma, who felt that their symptoms had improved.

Charity Asthma UK mentioned that the experimental tests revealed great potential and also be met with careful positivity. In UK, over five million people suffer from asthma, prolonged conditions that cause an affect to air passage in the lungs, causing cough, gasping and a feeling of breathlessness. For majority of the people, getting the right treatment can help keep asthma in check, like having inhalers. But, for some, the symptoms could be persistent.

Less puffing and panting

In 2014, according to Asthma UK, around 1,216 people lost their lives due to asthma. Likewise, flare ups can be fatal. In this experiment, specialist observed around 60 patients whose cases were severe regardless of consuming steroid inhalers, and visiting specialists.

Half of these people were administered the Fevipiprant pill for a duration of three months in addition to their standard prescribed medications, while the other half took their normal medication along with a placebo pill. Scientists found that, in patients who consumed Fevipiprant, there were fewer inflammatory blood cells in their air network and phlegm, as compared to those on normal medication, and proved to be a possible key sign of asthma. Gaye stokes has been suffering from asthma for the past 16 years quoted that ‘he knew immediately that he had been administered with that drug.

He felt totally different and was outgoing. He also felt less gasps and for the first time in many years he felt like he was fine.’ He also added that once she discontinued with the drug her asthma worsened again. Therefore, scientists say that this is yet an early evidence of the theory study and greater, prolonged trials will need to be conducted to find out if the pill can really come to aid to patient in daily life.

 In the interim, at Asthma UK, Dr Samantha Walker stated that, ‘ As this experiment is fixated on people who enhance the condition in later life, few of which we know can tussle with the efficiency required to use an inhaler, the likeliness of taking a pill instead of making use of an inhaler will be a very comfortable alternative.

There is a need for some more research for the same and there is still a long way yet to cover to see a pill for asthma made obtainable at pharmacy counters, then again it is truly a thrilling development.’ ‘Professor Chris Brightling’s group in Leicester offer convincing proof that the new tablet treatment has the capacity to decrease asthmatic inflammations, proliferating lung function and men asthma control in the severe group of people,’ said Professor Durham, a lung specialist, at the Royal Brompton

Hospital in London. He also mentioned that, ‘the data intensely supports additional studies to observe whether Fevipiprant possibly may reduce the occurrence of asthma attacks, dodge steroid tablet side effects and lessen NHS charges in the controlling of these severely ill asthma patients.

Thursday, 4 August 2016

Google Cardboard Saved Their Baby's Life


Google Cardboard Saves Life of Baby

Cassidy and Chad Lexcen, for the past six months have been too busy to look at the Google Cardboard images which had saved the life of their baby. At that time they had to look after their daughter who hovered on the threshold of life and death at Nicklaus Children’s Hospital in Miami. Besides that, they had to fly back and forth to take care of their three other children in Chaska, Minnesota.

However, CNN had recently brought the images of Teegan’s heart to the Lexcens and viewing them for the first time made them both happy as well as sad. Google Cardboard seems like a set of huge square goggles. You could stick your iPhone inside and with the appropriate app one can see images in three-dimensional virtual reality.

The paediatric heart surgeons at Nicklaus had utilised the Google Cardboard images in designing a one-of-a kind surgery for Teegan who had been born with half a heart and one lung. The doctors had not come across a child with the anatomy of Teegan in Miami and put in great efforts on what surgery could be helpful for her. Some of them thought of it as a hopeless case.

Images in Google Cardboard – Seen in Virtual Reality

However one member of the team, Dr Juan Carlos Muniz, had the inkling of viewing the images of her heart in Google Cardboard where it could be seen in virtual reality.Muniz had given the device to Dr Redmond Burke, the director of cardiovascular surgery at Nicklaus and he on utilising the device could move around and see the heart from each angle to almost the inside of the heart and could check its structure.

Google Cardboard enabled Burke to map out the surgery which was done in December and in July; her parents were able to see those images. Looking through Google Cardboard in his living room, Chad had exclaimed `Holy cow! This is cool!

It’s almost like a little video game’. Cassidy had added saying, `You don’t picture doctors and surgeons looking through a piece of cardboard and some glasses to plan a main lifesaving surgery. It seems like a toy’. Viewing the images had made the Lexcens appreciate much more the inventive surgery which had saved Teegan though it also brought back memories when her original doctors had informed them that their baby was in-operable and that the baby should be taken home.

Teegan Doing Well after Surgeries

Cassidy had stated that the doctors in Minnesota had informed them to make the best of their time with her and be ready to face her end. The most awful situation was when they had brought Teegan along with her twin sister, Riley back home and had to inform their older daughter, Harper who was then 6 years that Teegan was not going to make through her ailment.

They had to tell her that having two baby girls, one of them would be going to be an angel babyand Harperwas old enough to understand what an angel baby was, informed Cassidy. Nonetheless, the Lexcens did not give up but searched all around the country for a surgical team which would consider operating on their child. Eventually they located their team at Nicklaus and the surgery was conducted in December when she was nearly four months old. Even after the surgery, Teegan’s life still seemed to be vulnerable. She spent six months in the hospital and required two more surgeries inclusive of tracheostomy to aid her to breathe.

She was discharged in June and since then with the exception of a bad cold where she was hospitalized for some days, she has been doing well. Burke had informed them that Teegan needs to put on some weight since at 10 months she weighed only a little over 11 pounds. The Lexcan state that they will always be grateful to Burke and the other doctors and nurses who had taken care of Teegan as well as for Google Cardboard.