Wednesday, 26 April 2017

An old drug with new potential: WWII chemical-weapon antidote shows early promise as treatment for spinal cord injuries

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A New Medicine Built On Previous Grounds To Cure Spinal Cord Injuries.

A discovery in the field of medical science can never be forgotten, with new researches coming up in contemporary times; it may get old, but it will surely not lose its potential. Referring back to the old is a common phenomenon in every genre based on which new horizons can be explored.

Recent discovery has unveiled that a drug which was used during World War II to cure the pain and suffering that occurs due to severe injury taking place in your spinal cord. It works tremendously to retard neurotoxin that takes such a kind of injury to a different level of seriousness. This remarkable antidote is now leading to the evolution of a medicine that can cure several other injuries.

This drug is a potent suppresser of neurotoxin, also known as acrolein, that gets manufactured in our body when our nerve cells gets damaged and together with the formulation of neurotoxin if biochemical reactions also began to take place then your spinal cord’s injury will get worsen day by day. This is a very serious stage that can lead to paralysis if the seriousness of this injury is not brought under control. This can be life threatening as well.

The researchers have now discovered a new drug based on the same formula. Dimercapol is sure to keep in check all the toxins that builds up the chemical feature required for the formation of acrolein, instead transmits another toxin that will attack the toxins responsible for the formation of acrolein.

A professor of neuroscience and biomedical engineering in Purdue University, known as Riyi Shi; confirmed that Dimercapol is a very effective medicine that helps in eradicating acrolein and if fails to erase it completely then it helps in making the acrolein less toxic.

Shi has also confirmed that acrolein formation in the body has a severe drastic effect and leads to several other diseases to crop up. Pathologically it has a negative effect on your entire system and it also leads to health issues related to damaging of curtailing tissues, which in a way is responsible for the symptoms depicting serious illness. Sometimes the effects are such that it can lead to several other injuries in your body that has the capability to expand to the adjacent tissues.

Acrolein is responsible for disrupting a primary component known as lipids. The toxin is responsible for hampering lipids, which gets damaged because of the compounds, very commonly addressed as free radicals.

Free radicals are very dangerous for one’s health, as they are very reactive compounds to get generated after a trauma and leads to neurodegenerative diseases. Retarding of lipids is very close to several pathological problems occurring out of any severe trauma or diseases, the injuries and diseases includes spinal cord problems, traumatic injury of brain, several sclerosis and Alzheimer’s disease. The drugs that are responsible in performing the task of acrolein holders, is now considered as the most innovative strategy in keeping the concentration of neurotoxin under control.

Tuesday, 25 April 2017

Smart Tool Predicts Pregnancy Complications in Mothers

neonatal
Credit:Bridget Colla
Researchers at Queen Mary University of London had come together to develop which will help in saving both mother and babies lives. This tool effectively works by predicting whether the women in question are with early onset of the pre-eclampsia or are they fit to prolong their pregnancy. If you are wondering what eclampsia is then it is a condition which is known to affect as much as one per cent of the pregnant women and it is known to lead to extremely fata complication which might include the liver, kidney failure, lung problems, seizures and bleeding disorders.

How dangerous is pre-eclampsia?

Each year more than 1000 babies die due to complications rising from the pre-eclampsia. The PREP study conducted by team resulted in finding two highly successful method which helps in predicting the risk of the complications with an accuracy rate of the 84 percent among mothers. This research was funded by the National Institute for Health Research (NIHR) and it has already been published in the BMC medicine.

On the lead researcher associated with this study and development of the smart tool has stated that quite often babies are delivered prematurely which ultimately brings complications for the mother. Till today there is no robust test or guidelines to follow during the early birth scenario but the decision rest completely with the physician as well as mother in this regard.

It will be boon to the neonatal care

Currently the neonatal intensive care is in fragile state where one finds an acute shortage of the beds with higher hospital costs. Most of the hospital wards are concerned with the mother’s health and neonatal care takes a backseat. Secondly the cost of the facilities is so high that it becomes quite an expensive affair to check upon the pre-eclampsia tests.

Researchers had studied about 946 women who had shown the signs of early onset of the pre-eclampsia and they had been brought from 53 NHS trusts. Now the data was gathered for the participants through the team by carefully mentioning the age, gestation, blood pressure, liver & kidney function along with varied other parameters. The team of researchers were entrusted with the task of developing a mathematical model which will be able to predict the risk of complications in the participants who are the pregnant mothers.

How this smart tool works?

This tool has been named PREP model which will be helpful for the clinician in order to determine whether the mother is required to be transferred to the intensive maternal and neonatal care. The mother’s data and mathematical method will work together in analysing the mother’s health and it will help in figuring the high risk women from others.

Secondly the clinicians can make use of the PREP model in their regular practice through extremely well planned and robust clinical trials. This will help in understanding the subsequent rise of the pre-eclampsia among the pregnant women and it will also help in pre-emptive measure against it.

Friday, 21 April 2017

Zoonotic Diseases- An Assessment of Their Growth and Transmission

Poultry
When an infectious substance is transmitted from one creature to the body of human being, some internal processes are started. It is called as pathogenesis of viruses. This pathogenesis indicates the basic replication, which reaches the specific organs in our body. A procedure through which the replication of pathogen takes place is related to receptors, which are specific to the organs or cells. However, zoonoses demonstrate some intricate patterns.

Zoonotic disorders may be seen in almost any place. In most of the developing nations, they access our body through food chain, and then, they get increased in due course.

Zoonotic issues in different countries-

If you visit the UK and Vietnam, then you can see that people are now communicating or dealing with animals in the same way. On the other hand, in Mekong Delta, there is a very common scene, where people maintain vast range of livestock in a place, which is adjacent to their residences. In this country, uterus and blood of pig are often consumed in raw form. So, Streptococcus suis is the foremost reason behind a type of meningitis. However, there is a problem in the process of growing infections. It is not simple to predict of their development and the possibility of their response.

As lots of intricacies are present in the appearance of zoonotic syndrome, it seems to be impossible to identify the transmission at the initial stage in any animal or some human being. The main reason of more complication of the issue is that observation system is not good in many poorly developed countries. These countries are dependent on only healthcare specialists, who diagnose the problem.

How the infections can be diagnosed easily-

The best fact is that with the help of zoonotic possibilities of any animal, it is easy to recognize them before they are transmitted to our body. But, for some reason, if this is not accomplished, everyone must be conscious of those infections. As soon as the infection has been diagnosed, all people have to be treated without delay. The seriousness of the condition is also to be analyzed with the clinical experts.

Diagnostic data is highly important to know about the transmission of Shigella sonnei. People, with serious diarrhoeal disorder, have such organism. At the time of scientific observation, it has been noticed that Shigella considerably resists fluoroquinolones, which are often used for treating infection.

All the findings from research were much unexpected. Such approach may not be a good strategy in the long run to prevent or observe any pathogen. Lots of improvements are needed in infrastructure in order to have a better model, mainly in low developed nations.

Since 2007, Vietnam already has started showing some changes. Stability in political domain and investment of economic asset has good results in the field of healthcare. However, still, there are lots of challenges. Southeastern regions of Asia are the major areas, where lots of steps are taken to secure the health of people.

Wednesday, 12 April 2017

Researchers Develop New Solution for Independent Living: the ‘Empathetic Home’

Empathetic home to give more independence to the senior citizens

We know that with an increase of our age, we need special care to maintain our body. In some cases, the family members give an extra attention to their aged relatives. Sometimes, caregivers are also employed to look after the elderly people. However, now, it has become much easier for anyone to care for the aged persons.

TU/e is going to introduce a new way of living independently. The researchers of this university have suggested a special type of environment, which is called as empathetic home. This special setting is named so because it empathizes with elderly residents of a house. The technology, involved in it, works as a caregiver. According to the explanation, provided by the researchers, some sensors are to be installed on the floors and walls.

Best home for handicaps and aged persons-

The scientists have planned for this environment, considering the fact that lots of citizens in Netherlands are ageing. If we look back at the year, 2013, we may see that the age of more than 2 million people is over sixty five. It is assumed that by the year 2030, it will reach almost 4 million.

 That is why some guidelines are also given from government in order to allow the aged persons to survive independently. In case of handicaps also, the settings must enable them to spend time in a standard environment. But, the main problem is that there are not enough accommodation units, which are compatible to fulfill all the diverse needs of elderly citizens.

Empathetic home does all your jobs-

Masi Mohammadi, one of the members of TU/e, has said that a good home should offer not merely a roofing structure over our head. It’s really a good idea, if that house takes the responsibility of giving care to all the senior inhabitants. Masi also added that the empathetic design of home has the ability of recognizing the residents and giving them response to their requirements. It also helps people to do workouts and provides them with customized care to ensure healthy life.

The main target with empathetic home is to make the room automated. The technology, relevant to it, is referred to as smart. And it is to be integrated flawlessly to your house. It is also possible to regulate the requirements of all residents and to support them in their everyday activities.

Regions selected for testing the new home-

Masi Mohammadi has decided to express her own vision about the special home. That is why she wants to test out some concrete components, which are to be added to your home. However, there should be an exceptional association with 3 advanced centers, which are in three regions, Hertogenbosch, Roermond and Eindhoven zone. These are labs, where the output of this new innovation will be researched thoroughly.

The concept of edible wall is to be launched. It’s a wall with vertical garden that comprises herbs. Seniors do not need to give much effort for gardening. Besides, the smart flooring also allows prevents the possibilities of slip and fall accidents.

Tuesday, 11 April 2017

Brain's 'GPS' Does a Lot More Than Just Navigate

Well, the most important part of our body is nothing than the brain. Often it is termed as the CPU of the body as it helps in taking decisions and thinking. Without the brain, a person is useless. However, the brain does more than just navigating or helping us to learn. The recent study or the report from the scientists have revealed that the region which helps in spatial navigation also help in cognitive navigation. Well, this is indeed a wonderful discovery by the scientists.

THE STUDY

The recent study by the scientists revealed that a region in the brain called the hippocampus becomes active when the rats move around the environment. All that research showed that the cells in the entorhinal cortex fire when the creatures reach a certain specific location. This has led to the discovery that the brain creates a mapping of the outside environment on its own.

 This is like a mental positioning system to help the animal identify where its location is in the environment. The famous researchers in the Princeton has found that the same regions of the brain are active when the brain is roaming in the different kind of environment.

It may also take the sounds into consideration. The experiment was done with the help of the rats. They found that the rats responded to the different sounds after listening to the sounds and it matched with the similar traits when the rodents were roaming in their own backyard.

THE MYSTERY

Well, it is a long mystery in the field of neuroscience that how the part of the brain called hippocampus could relate by mapping the external environment and also in creating memories. If the people have a damaged hippocampus, they are unable to form memories which is a major drawback for the people.

The researchers state that the combination of both hippocampus and the nearby entorhinal cortex help in making maps which are cognitive in nature. They involve tasks like memory and learning.

When the rats were given a different task like reconnoitering, the researchers have found some unusual evidence in the circuit of the hippocampus and the entorhinal cortex. They have chosen as the parameter to experiment.

THE MONITORING

The researchers then monitored the activities of the rats specially the electrical activity of the neurons present inside the brain. They found that the rodents were able to relate the sounds along with the frequency. The rats were trained to do some specific tasks like pulling the lever down bases on the sound frequency. After the performance, the rats knew that they would be rewarded.

This helped them to perform the tasks in the most efficient manner. The observing team found that the patterns of the neuronal triggering along with their behaviour. Slowly they advanced with the frequencies which were similar with the revolving around in the space.

Finally, it was concluded that the hippocampal cells become active when they are in a particular place and the entorhinal cells come into picture when the rodents travel through some specific places or locations.

Monday, 10 April 2017

Modeling the Female Reproductive Tract

EVATAR
With the ever increasing and developing folds of science has suggested the fact that there is nothing in this world that can spare itself from the spell of scientific innovation. The scientific discoveries and researches are going to the extent of erasing the world of impossibilities. Soon there will be a time when there would not be any question whose answer will not be there with science. May that be any serious disease or any natural calamity everything can now be subjugated with the notches of scientific evolution surpassing all levels of revolution.

Menstruation is very common to every woman. It is a natural phenomenon that will take place in every woman’s life at the appointed time. There are only few who remain unattended by this natural occurrence. In Chicago one of the Northwestern medicine has revealed the fact that a female reproductive organ can be developed that is small enough to fit in the hands and has the capability to denote the future of research leading to curing of several diseases that occurs in a female reproductive organ. It is sure to make every impromptu situation change into an intended reality.

The scientists have named this scientific innovation EVATAR which based on technology and comprises of tissues of humans that will simultaneously lead to testing of the sustaining capacity of every new drug, to project how much reliable the medicine is to affect the reproductive system of a female.

EVATAR is also said to grasp the pulse of very disease that can occur in a female reproductory organ, measuring the intensity of diseases like endometriosis, fibroids (which is most commonly found in maximum women), cancer and even infertility.

The scientists have got the idea of this terrific revolution is by using the cells of an individual that will lead to the formation of an identical model similar to their reproductive system. EVATAR is said to comprise of ovaries of 3-D models, fallopian tubes, uterus, cervix, vagina and even liver that contains a unique kind of fluid that will pump blood from all the other parts mentioned so that the desired function can be performed. This EVATAR has a structure that of a cube which is not at all big.

The lead founder of this scientific innovation known as Teresa Woodruff, who is a named scientist of reproductive organs and also the director of the Women’s Health Research Institute; situated at Northwestern University Feinberg School of Medicine, suggests that this is no way a revolutionary innovation; rather she claims that this evolution is entirely based on the pre-existing theories of technology that sustains the whole idea of artificial formation of a naturally existing norms to deliver a natural result from all perspectives that will also cure several other diseases and problems that a woman has to go through just because of a natural formation that takes place in her body on which she does not have any control. She will have to accept what comes to her may that be good or bad, but due this innovation some problems can at least be dealt with if not all.

Wednesday, 5 April 2017

The Microbes in Your body That You Couldn’t Live Without

Microbial Life – Inside the Bowels

When Adam Rutherford took an uncomfortable test he discovered that for a healthy body full of good bacteria, one would need to do much more than consume probiotic yoghurt. It started off with what could be defined as an creative invention with a fold-out sheet having sticky tabs towards the front and back just like a flattened starfish. The tabs stick tend to stick to the seat of the loo and when it is in place, it is said to form a kind of hammock on which the specimen is offered, set for sampling.

He had slipped on the rubber gloves in preparation for the process. When he had left the deposit on the hammock a sample of the stuff with a small spoon attached to the inside of a blue lid of a test tube and wrapped in an icepack which was frozen earlier was dispatched - `Map My Gut which revealed what microbial life seemed to be inside the bowels.

Recently, numerous findings have indicated that the microbes in the digestive system seem to be more significant to our health and well-being than earlier presumed. On an average, we tend to have around one thousand different species of bacteria in our guts and in total though difficult to count could be around trillions. Most of it has been doing beneficial for us.

Microbes Help to Build Our Bodies

It is said that our genomes comprises of about 20,000 genes though our microbes tend to carry about 500 times more. This enables them to perform some tricks, they help to digest food, produce vitamins and minerals and even prevent us from suffering from some disorder by crowding and killing infectious bacteria. Moreover, they have also shaped who we are on the inside as well as the outside.

 Ed Yong, author of I Contain Multitude informs that our microbes help to build our bodies; they tend to sculpt and renew our organs as we tend to age. Besides, they may also influence our behaviour and the way we think. There have been several studies in animals portraying that microbes in the guts could influence their mood, personality and resilience to anxiety and stress.

But how much of these effects would carry in humans is still to be understood. However, we do tend to be aware that there is a much larger variation between people in our microbiome than there is in our genome.

Fermented Food – Healthy Microbiome

Makeup of our microbial is based on our medical history, our diet and our location. It is said to be a signature which could be very different to even our nearest relatives. Less than 100 species of bacteria tend to cause infectious disorder and the thousands of kinds of microbes located in our guts are according to author Douglas Adam, `mostly harmless’.

Top of the list of the most desirable are microbes such as Akkermansia and the Christensenellaceae which have been linked with protection against weight gain. Methanobrevibacter is said to be helpful in squeezing more calories from food which means that one could eat less while Oxalobacter tends to be helpful in the prevention of formation of kidney stones. For a healthy microbiome, fermented food is said to be especially good.

Monday, 3 April 2017

Scientists Identify Brain Circuit That Drives Pleasure-Inducing Behavior

Brain
Amygdala is that part of our brain which balances memory, emotional reactions and decision making processes and is responsible for making us stressed when we have that really important, or not so important, exam coming up. At least this is the train of thought scientists followed till the last 22nd March.

Graduate students Joshua Kim and Xiangyu Zhang authored a paper on an experiment supervised by Susumu Tonegawa, the Picower Professor of Biology and Neuroscience and a director at the RIKEN-MIT Center; which sheds new light on the activities of amygdala and show that they are hugely responsible to generate the happy feelings you get while biting on the piece of dark chocolate.

The experiment

The past body of research had been dedicated to unravel the circuitry of the brain from where negative behavior seemed to stem. Tonegawa and his team of neuroscientists from MIT conducted a groundbreaking research which has succeeded in confirming that amygdala consists of both reward and fear circuitry and is intricately involved in generating positive emotions.

Amygdala changed from the fear center of the brain to the reward generator in the experiment carried out by Tonegawa’s team on mice.Infact this research is a continuation of last year’s work where neurons from Basolateral Amygdala were thought to relay positive and negative information to nucleus of central amygdala.

Initially the central amygdala neurons were mapped into seven groups depending on the kind of genetic expression they point to. Then the mapped regions were exposed to optogenetics which basically uses light to control neural activity. What emerged from the experiment was five regions out of seven imitate reward related behavior which drove the mice to expose themselves more to light source. One region was found to be associated with fear related behavior.

Though about 90% of discovered amygdala tissue has been found to contribute to positive behavior, about 10% is still undiscovered and unmapped and according to Tonegawa the neural circuitry in the uncharted regions may be responsible to trigger negative emotions.

Generally, an amygdala can be said to exhibit appetitive behavior catering to satisfy the specific drive at an instant.

Aftermath of the experiment

The basolateral amygdala is being studied for the role it plays in fear extinction, which basically is a process used to overwrite the existing sets of fearful memories and replace it with positive ones and is used to treat cases of depression, post-traumatic stress disorder etc. Since the misconceptions about central amygdala acting as seat of negative stimuli has been invalidated, a new region called periaqueductal gray has emerged as research favorite to locate the pain and fear related stimuli.

The success of the experiment lies in firmly establishing the amygdala as a seat of positive stimuli and refuting its image as the fear center.Scientific community is elated at the new unexpected set of discovery. Scientists not officially related to the experiment have been quoted to find the new information to herald exciting times for brain research.

Saturday, 1 April 2017

Virus Hydrophobicity Can Help Purify Vaccines

Hydrophobicity
We usually try to detect virus in our body, whenever we become ill. However, now with the development of medical field, some researchers have found out a new way for recognizing virus easily by looking at the external layers.

A virus has a very intricate structure. On surface area of all viruses, there are tiny knits of some proteins. And these are mainly responsible for the serious effect, created by virus after having an interaction with our cells or the favorable environment in the surrounding area. If there is any alteration in the series of protein, then the surface turns out to be hydrophobic. It means that the part may repel water, and as a result, a sticky substance is formed on the surface.

One of the members (Heldt) at chemical research department of Michigan University has stated something about the new innovations of the researchers. At present, many of the associates of this University are trying to have a concept on how the hydrophobicity on virus surface is to be applied for the improvement in the production of vaccines.

A comparison on a variety of results-

Heldt has also claimed that dealing with purification of vaccine means working on the interactions on surface. While there is a disintegration of all components, they may not be applied as a kind of remedy. In addition to it, identification and removal of viruses also have a direct relation with all these interactions. Such facts may be very useful to the experts to know the interactions of virus or germs with our cells. The good news is that Caryn Heldt as well as her associates has made a comparison of different computational and experimental techniques in order to know the chemistry of surface.

Hydrophobicity- How the researchers tried to identify it-

Hydrophobicity may be defined as a property, which is found in a molecule that seems to be repelled or resisted from water mass. As the hydrophobicity of virus is quite tough to determine, the associates of Heldt emphasize the use of hydrophobicity pattern. These experts have also evaluated the possible measurements of hydrophobicity on the basis of protein, present in virus. They have tested out the specimens with the application of two chromatography types. One is the blend of chemicals and another one is fluorescent tints, which cause the appearance of hydrophobic, gluey spots on surface of proteins. The main fact is that all measurements try to make out something, which is easily accessible.

According to Heldt, the capsid of virus is so big that it is intricate to do measurements. To clarify the issues, Heldt has explained that capsid refers to outer shell, which comprises sixty same types of proteins, such as, VP1, 2 or 3. Heldt along with other researchers has tested VP2 and its exposed areas. There is a good link among all the results. And it reveals that any virus, including PPV has hydrophobicity, which is easily assessable. After having a better understanding of these measurements, the researchers may be able to detect virus.

Monday, 27 March 2017

Fruit Shaped Sensor can Improve Freshness of Fruits

Fruit Shaped Sensor
The main issues cargo companies face while shipping fresh fruits is the degradation of the cargo contents. Various factors can be responsible for fruits losing their freshness, contamination by bacteria and temperature being the primary causes. Fruits have to travel a long way before they reach shops and eventually to our homes. Not every cargo does reach safely; most of them perish on their way resulting in heavy losses to both suppliers as well as customers. To deal with this problem, researchers from Swiss federal laboratories for material Science and Technology have come up with a sensor device that looks exactly like a fruit!

The basic idea behind this sensor is to inform the transport firm about the conditions inside the cargo and if there is proper cooling. If any irregularities are found, the sensor alerts the firm to take immediate action. The device is identical to different types of fruits which include apples, oranges, bananas and mangoes at the moment. These are to be kept in with the real fruits inside the cargo container which in turn monitors the temperature.

Causes of spoilage

Temperature and external factors play a major role is spoiling the freshness of fruits. Cargos containing the fruits are often kept outside during layovers or change of transport. This can cause the contents to be exposed to external environmental factors such as heat and also different airborne microorganisms. Another cause can be attributed to power cut offs in transport or storage units which can affect the quality of the fruits being delivered. Exporters often use sensors to keep informed about the cargo temperatures but it can only give a generalized temperature reading. this is new sensor which is still in its trial days is more capable than its other counterparts as it can effectively simulate different characteristics of individual fruit types and give a detailed reading.

The making of the sensor

To prepare the device, researchers, first did a full x-ray of real fruits- apples, oranges, bananas and mangoes. The sensor devices were modeled exactly based on the texture and shape of the fruits.

The teams then went on to find out the composition of the fruits and were able to recreate each of the different fruit’s flesh by using a mix of carbohydrates, water and polystyrene.

Fruit shaped molds were then created using 3D printers and the mixture were poured and allowed to take the shape of the fruit. Sensors were fitted in the middle of the fruit molds.

The sensors would control the temperature data and readings for the whole transport process. If something goes wrong during the journey, suppliers can work out a solution from the temperature readings. Researchers are performing successful field tests and it won’t be long that these fruit sensors are commercialized, to be used by both big and small transit firms. The team hopes to reduce the cost and time of the logistics operation and help companies make amendments to sanitary protocols.

Premature Babies’ Brains Respond Differently To Gentle Touching

Premature Baby
The greatest pleasure and happiness in this world that a woman gets is when she gives birth to a baby. Well, that bliss can be understood and felt by the mother only. But often the woman has to undergo many pains and sufferings for giving birth to a baby. Well, the report states that premature babies’ brain respond differently to gently touching. This has been revealed after a lot of study and experiments. The babies that are born before the normal gestation period that is almost close to 40 weeks show different responses ranging from the sensory movements to emotions.

THE DIFFERENCE

Well, the babies which are within 36 weeks and do not stay for 40 weeks in the uterus of the mother show different signs of response. However this gets reduced with the regular skin contact with the mother and also the amount of time it spends in the hospital where the staffs take the utmost care of the baby. They have to bear the brunt of getting pre delivered. Often they have to put under ventilation and also some undergo operations which are pretty painful. They experience some greater force of gravity on their tissues and muscles. Well, it has been found that such painful experiences in the early age can affect in the development phase. This would create a difference between a normal baby and pre matured babies’ brain.

THE STUDY

The pre matured babies’ brain would have some long term alterations. A light touch is quite different than that the baby suffers due to a pain. A recent test was conducted with the two types of babies by putting electrodes on their body and it was found that pre matured babies’ brain have a different response with that to the babies who were born after the normal gestation period. It takes time for the receptors to get activated in the pre matured babies. Normally the touch and hearing sense organs get activated in the babies. The processing of the brain is a bit slow in the pre matured babies.

THE COMMUNICATION

The babies who have spent more time with the mothers responded differently to the ones who have to spend time in the ICU. Well, it is still unclear whether the pattern of responses in pre matured or the normal babies are become same in the later stages of life. If the touch and hearing response develop some problem, then it is a matter of great concern. It is the exposure to the gentle touch that ultimately matters in the response of the brain of the pre matured babies. Nothing has been confirmed yet of what causes these unusual responses. However, the experiments are going on. It is normally recommended that the mothers should be aware that the skin –to-skin touch with the babies will have a great impact in the positive manner. So, the more frequent touch is with the baby, the better the pre matured babies’ brain would respond to the environment and other feelings.

Friday, 24 March 2017

Pink Noise Can Improve Sleep and Memory in Seniors

sleep

Sound Essential in Assisting to Get Good Sleep

The sounds of rushing water of a waterfall, the regular beating of a heart or the sound of rain are usually found in white noise machines which have been designed to assist babies to fall asleep. According to a new Northwestern University research, sound is said to be an essential element in assisting us to eventually get into a good night’s sleep.

Moreover, it also tends to develop memories. As per a study published recently in the journal Frontiers in Human Neuroscience, a simple non-invasive, non-medical safe and economical means of getting a much improved sleep at night is to play some pink noise. Pink noise is said to have lesser octaves when compared to typical white noise and is not much soothing. For instance, it could be one-second pulses of the sound of rushing waterfall.

The small parts of quiet, quick sounds would tend to be disturbing should one decide to fall asleep.. However, the pink sound is not attempting to get one to fall asleep but would attempt to put you into a deep slumber wherein one would have slow brainwaves. This is said to be one of our deepest means of sleep which tends to weaken in the case of aging adults.

Sound Therapy – Quality over Quantity

According to Nelly Papalambros, a PhD student at Northwestern University as well as the first author on the work, states that when one plays the pulses at specific times at the stage of deep sleep, it tends to lead to an enhancement of the electrical signal, leading to essentially more of a synchronization of the neurons.

The pulses are said to be timed to correspond with the entry into slow wave sleep. They tend to sound to similar beat as the brainwaves and are inclined to increase the efficiency of your valued as well as elusive deep sleep. The relaxed wave sleep is dangerous for retention associated or essentially, your capability in incorporating new material studied during the day with old material as well as memories.

The sound therapy is not about actually sleeping deeply for longer period but about quality over quantity. One may not be quite rested yet would be remembering more. The researchers observed only the older adults in the age group of 60 plus and had 13 volunteers and did a memory test at night.

Word Association Recall Test

The procedure seemed to be quite simple wherein they attempted to memorize associated words such as oil and energy, or marriage and altar. They were then tested to check how much of it they had recalled before they had dropped off to sleep. The next day the participants were once again tested to see how well they had recalled their training from the previous night.

The word association recall test scores seemed to be thrice better if the participants had the pulses while sleeping than if they had a fake treatment. The team that had obtained the fake treatment seemed to have the same sleep routine and did not get the faint pulses of sound when they had been in the stage of slow wave deep.

The reason to consider older adults was because as one tends to age, sleep seems to become more broken. One does not seem to have much slow wave sleep which then leads to memory loss.

Monday, 20 March 2017

LSD Could Actually Heal the Brain

LSD
Mental Illness Treated as Binary Condition

As per World Health Organisation, over 300 million people from all age tend to suffer from depression. The UK Charity Combat Stress, an organisation that tends to render support for British military personnel, lists alcohol misuse, panic attacks and PTSD are the common mental problems envisaged in returning soldiers. Unlike physical illness, mental illness has been treated as a binary condition wherein the person is well or not. Diagnosis of mental illness seems to be extensive and affects several people and as it tends to grow so does the cost of treatment for the same.

According to public health specialist and mental health advocate, Khaliya, for several years, mental health has been spoken about partly since the tool available seemed hard to scale and partly since some of the most powerful tools with regards to health of the brain were stigmatised and turned into scheduled drugs, effectively halting any progress that could be made to prove its efficacy.

 The drug he has been referring to seem to be psychedelic compounds such as Psyciliciban, LSD MDMA, Ayahausca and 5-MeO-DMT. He further added that in the past few years, the research in these drugs though mostly small scale studies, seemed to have remarkable achievement.

Psychedelic Drugs – Treating/Healing Brain

Researchers are of the belief that a single dose of psychedelic drugs could be beneficial inimproving the symptoms of some of the common illness of the brain. They are hopeful that they would eventually be capable of not only treating but actually heal the brain.

Khaliya, while talking at WIRED Health in London had spoken about her own mental health problem stating that she is literally healed today and is grateful for every day and for having a second opportunity at life and is one of the lucky ones.

 The people who tend to need this the most do not have enough money to wait for decades. Brain problem have been presently the main issue of suffering all across the globe. Between 2011 to 2050 the collective output loss of global economic related to mental health disorders is said to be about $16.3 trillion thus making the economic output loss equivalent to the complete GDP of the United States.

Dementia/Stroke on the Rise

Besides this, dementia and stroke is also on the rise and these figures seem to be shocking and distressing considering the various probable effective treatments. These are not being implemented and are not being effectively researched due to cultural and not medical reasons. The most annoying thing with regards to health care industry is that it does not tend to connect to most of the powerful weapons which is the human body.

With respect to the brain this is psychedelic compounds and relating to the body, connecting the power of stems cells.Most of the organisation do not tend to work sincerely and often resort in earning extra money without rendering the appropriate treatment, resulting thus in prolonged illness of the patient. Treating the disorder with the much needed treatment could help the patient both financially as well as mentally bringing about much relief to those who have been the victims of this depressing disorder.

Saturday, 18 March 2017

5 Essential Tips for Expectant Indian Women

Expectant Women

What You Must Know Before Baby's Birth?

Expecting a baby is the most wonderful feeling in this world. You will experience a mix of emotions during this phase. Sometimes you feel happy while sometimes you feel scared because of the future challenges.

Sarah Walker, an artist, once explained her feeling that

“Becoming a mother is like discovering the existence of a strange new room in the house where you already live.” 

When the baby arrives, you want to give every comfort of this world to make sure he/ she is safe. With a different level of responsibilities, you start planning your schedule and make yourself prepare for coming responsibility. But, in the hustle-bustle, you may forget many essential things. Hence, it is a must to start making a to-do list a month or two before the delivery to eliminate the last minute rush.

Here, we have shared a short list of important tasks that an expectant mom must consider before the childbirth.

  1. Shortlist Few Baby Names 

    When a baby arrives, people give several random and irritating names.

    Obviously, you won’t like to call your little one with some crazy name, right? So, make a shortlist of cute Indian Baby Names before the childbirth. Select the most appropriate one after the birth.

  2. Workout/ Exercises for Natural Baby Birth

  3. If you want to avoid a C-section and your pregnancy is normal then exercises are beneficial to avoid complications at the time of delivery. But that doesn’t mean heavy and long exercise sessions. There are some special exercises for increasing chances of normal delivery, for that do consult with your doctor. Yoga postures are effective and safe also they help in reducing the aches and preparing body for easier childbirth.
    Expectant Women


  4. Prepare Hospital Bag One Month Prior

  5. The delivery timing is always uncertain. Hence, start making a hospital bag of essentials a month before, is always helpful. You can take help from a doctor or an experienced mom to make a list of essentials and "Buy newborn essentials online in India."

    Make sure you won’t skip any important item.

  6. Read the Breast Feeding Guide

  7. Nowadays, the majority of couples live away from their families. Hence, it is become more crucial to stay updated with all the information related to before and after the childbirth. You can easily get the details online as the Internet is the pool of information.

    Breastfeeding has many advantages. Alongside, moms and babies may face issues if not supervised correctly. Hence, mom should know what’s necessary and what’s not during breastfeeding.

  8. Find A Pediatrician

  9. Babies are fragile and easily prone to infections. They need a lot of care and precautions at every stage.
    Finding a pediatrician may seem a premature decision, but it is for the benefit of you and your baby. Right after the childbirth, you will require a pediatrician to know what the perfect diet for a newborn is and how much you should feed. What’s good and what’s bad for a baby can only be figured out with the help of a pediatrician.
Hence, it is necessary to stay in touch with a good pediatrician near your home.

While choosing a pediatrician, consider a few things such what are their hours? What is their philosophy on vaccinations?You can ask for suggestions from friends and family members who have children. Make an appointment and visit their clinic to know more about them. It is always a good decision to explore a bit about the pediatrician and the staff.

Conclusion- An expectant mom should consider a few things for hassle-free childbirth. They can either consult with a doctor or an experienced mom to avoid all mistreatments. Read the article thoroughly to have a healthy and happy baby.


Author Bio: Sapana is mother of 2 and a WAHM IT Professional. She writes about pregnancy health, breastfeeding and baby health on her blog: www.gomama247.com

Saturday, 11 March 2017

This AI Doctor Knows What's Wrong With You By Checking Your Genome

Genome

Sequencing of Genome – Decoding DNA

A Swiss based Sophia Genetics, Camblong has been attempting the possibility to democratise data driven medicine by standardising the data analytics all across the globe. Initiated in 2011 it has been trying to do the same with the help of artificial intelligence together with machine learning. Speaking at the conference of Wired Health, in London, Jurgi Camblong had announced that within the following few weeks the firm would be analysing the genomic profiles of 100,000 people.

The sequencing of genome is said to be the practice of decoding the DNA of a person which is a procedure that tends to generate massive extent of data. Each person’s genome comprises of 3.2 billion letters of DNA containing around 20,000 separate genes. The genomic program at NHS has been focusing to sequence 100,000 genomes all over England, wherein beginning of March, it had completed 20,000. On completion, it stated that the data would come in at 31 petabytes.

 In order to get an understanding of the scale, one petabyte of music would be taking about 2,000 years to play. In his firm’s SOPHiA artificial intelligence, which tend to learn from the genomic profiles of patients, Camblong had mentioned that it had already been utilised in supporting the diagnosis of 100,000 people.

AI – Hospitals Receives Actionable Insight

By utilising the AI, hospitals have been capable of receiving `actionable insight regarding patients which enables doctors in comprehending the cause regarding the diseases. It has been mentioned by Sophia Genetics that it has been operating on five areas namely oncology, hereditary cancer, cardiology, metabolism and paediatric conditions.

Camblong had informed that the more data SOPHiA tends to process, it learns more, since information is constantly shared secretly on the platform in order to assist clinicians to enhance individually thus making improved decisions. The scheme tends to function by observing the genomic profiles of each individual, combing it with the information of doctors as well as clinicians.

With the help of machine learning, the more date system is fed, the better is the decision it tends to make. The business model tends to work by charging the hospital every time it utilises the tool. Camblong debates it is so because his firm is capable of computing data better than the hospitals it sells to.

Future - Chronic Disorder

Presently the software of the company is being utilised in around 250 hospitals in 45 countries all over the world which comprises of 10 NHS hospitals in the UK. This is said to be twice the number of hospitals which had been utilising the software beginning of 2016 according to Camblong’s information to WIRED. Neither the firm nor the NHS is the only one interested in processing genomic sequencing.

 Google in the earlier years had been approaching hospitals as well as universities, proposing them its cloud services in order to store genome data in the cloud. The cost presently is around £1,000 in order to sequence the genome of a complete person. However, when it had first sequenced in 2000 the cost was about $100 million.
According to Camblong, the downward trend would continue as the amount of data and knowledge will increase and in time that cost would drop to $100.Camblong is of the belief that in the near future, cancer would be considered as a `chronic disorder and hopes that it would be possible to look at this disease and say that it looks like the cancer of 10,000 other patients’, providing advice to doctors for the treatment of the same.